The significance of different formulations of aerosolized colistin

نویسندگان

  • Argyris Michalopoulos
  • Sofia K Kasiakou
  • Matthew E Falagas
چکیده

We thank Dr Mubareka and Dr Rubinstein for their thoughtful commentary [1] related to our recent publication on aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis [2]. We would like to provide some additional clarifications related to the formulation of colistin used in our study because the commentators state that “... it is not clear why the more toxic form of colistin was chosen over the better-tolerated colistin sulphamethate”.

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عنوان ژورنال:
  • Critical Care

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2005